Circos > Citations

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Circos Opens Our Eyes to Cancer Research

The rise of cheap and rapid genome sequencing has allowed for individual cancer genomes to be sequenced and compared to the reference human sequence. This comparison includes enumerating structural differences, as well as spatial characteristics across the genome, such as gene expression and methylation levels.

Circos is currently one of the standard methods to visualize these data.

End-joining, translocations and cancer (969 x 433)
▲ Nature Reviews Cancer article End-joining, translocations and cancer by Bunting and Nussenzweig discuss the mechnisms behind genomic rearrangements and show how Circos can help visualize them.
The Cancer Genome Challenge (969 x 431)
▲ Nature features an article by Heidi Ledford, The Cancer Genome Challenge, which reports on the progress and challenges of identifying structural variation signatures in cancer genomes.

Circos in the Literature

My images created with Circos have appeared in a variety of scientific, general and book publications, such as Wired, New York Times, Conde Nast Portfolio, and American Scientist. publication-logos

Circos in Bioinformatics - Circoletto Circos in Genome Biology - Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors Circos in Nature - A first look at entire human methylomes Circos in Science - The B73 Maize Genome: Complexity, Diversity, and Dynamics Circos in PNAS - A Nitrospira metagenome illuminates the physiology and evolution of globally important nitrite-oxidizing bacteria
Circos in American Scientist - Genetics and the Shape of Dogs Circos in Genome Research - Automated identification of conserved synteny after whole-genome duplication Circos in Conde Nast Portfolio - 23andme Circos in Wired - Getting Lost Circos in PNAS - A Nitrospira metagenome illuminates the physiology and evolution of globally important nitrite-oxidizing bacteria
Circos in PLoS - U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
Circos in Plant Cell - Fast Diploidization in Close Mesopolyploid Relatives of Arabidopsis Circos in New York Times - Now, for the rest of the genome New insights to the MLL recombinome of acute leukemias Circos in SEED

In genomics, scientific journals like Science, Nature, PLoS, Genome Research and others have published papers that used Circos images (scientific citations).