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Circos Opens Our Eyes to Cancer Research
The rise of cheap and rapid genome sequencing has allowed for individual cancer genomes to be sequenced and compared to the reference human sequence. This comparison includes enumerating structural differences, as well as spatial characteristics across the genome, such as gene expression and methylation levels.
Circos is currently one of the standard methods to visualize these data.
Nature Reviews Cancer article
Cancer Genome Challenge
, which reports on the progress and challenges of
identifying structural variation signatures in cancer genomes.
Nature features an
article by Heidi Ledford,
Circos in the Literature
My images created with Circos have appeared in a variety of scientific, general and book publications, such as Wired, New York Times, Conde Nast Portfolio, and American Scientist.
In genomics, scientific journals like Science, Nature, PLoS, Genome Research and others have published papers that used Circos images (scientific citations).