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Circos at the EMBO NGS workshop in Tunis, Sept 15–25.

Little Fly, Thy Summer's Play...

In a collaboration with Derek Baccus from Pearson Science, Martin Krzywinski designed the cover illustration for the 3rd edition of iGenetics by Peter Russell.

The cover image shows a comparison of human and fruit fly genomes. The links indicate orthologous genes — genes in both genomes whose proteins are similar.

This cover won the cover award at 39th Annual 2009 Bookbuilders West Book Show.

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

The task was to visually represent about 60 relationships shared between 35 characters. The tableviewer utility, which applies Circos to visualizing tabular data, was perfect for creating the illustration. And thus, Circos says goodbye to the table.

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

The task was to visually represent about 60 relationships shared between 35 characters. The tableviewer utility, which applies Circos to visualizing tabular data, was perfect for creating the illustration.

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

In collaboration with Christy Sheppard, Wired's Art Director, Martin Krzywinski created the illustration for the April 22 2010 issue.

Circos Introduced in the New York Times

My first Circos infographic to be published in the New York Times introduces the idea of sequence similarity curves linking circularly composed ideograms.

Working with David Constantine, I illustrated the similarity between chromosome 1 of mouse, rhesus, chimp, and chicken to that of human.

One of the smaller panels in the infographic was subsequently used by the Alliance of Lupus Research in their Faces of Lupus II video.

Circos Sniffs out Dog Genetics in American Scientist

The completion of the draft version of the dog genome revealed large overlaps between dog and human genomes. Working with American Scientist, Martin Krzywinski generated an illustration showing blocks of similarity between the two genomes.

The illustration accompanies the article Genetics and the Shape of Dogs, by Elaine Ostrander.

NYT Article - Mapping the Epigenome

In collaboration with Jonathan Corum from the NYT, Martin Krzywinski created an illustration of data showing methylation on chromosome 22 in a variety of tissues.

The illustration accompanies the article Now: The Rest of the Genome, by Carl Zimmer.

For other references to Circos usage and items of note, see examples of published images and Circos citations.

News



28 April 2010

In 2008, I worked with Pearson publishers to create a cover for iGenetics (3rd ed) by Peter Russell. I just received a copy of the award won by the book's cover illustration.

Circos iGenetics book cover - recognized at the 39th annual Bookbuilders West Book Show (781 x 400)
12 April 2010

In collaboration with Wired, I created an infographic that illustrates the relationship between characters on the TV show Lost. The image appears in the 22 April 2010 issue of Wired.

Circos - Circular Genome Data Visualization (800 x 424)
6 April 2010

Last year I collaborated with Derek Baccus from Pearson Science on a cover illustration for the 3rd edition of iGenetics by Peter Russell. I have just learned that this cover has won an award from Bookbuilders West.

A book cover that I created with Circos has won the Bookbuilders West Cover Award (500 x 569)
11 January 2010

I've received a copy of the beautiful book Expedition Zukunft/Science Express. I've written previously about this great science education project.

Circos - Circular Genome Data Visualization (600 x 441)

Circos - Circular Genome Data Visualization (600 x 472)
2 November 2009

I've just received news that the Chromosomes exhibition by David Cronenberg, which uses Circos illustrations and my contribution to text, will be staged in Estoril (Portugal) during the film festival.

Circos - Circular Genome Data Visualization (600 x 600)

The project also toured in Rome, Turin and Lisbon

The Film Festival of Estoril and Volumina are pleased to announce the new staging of multimedia exhibition CHROMOSOMES by David Cronenberg. During the opening (november, 10) will be present Cronenberg, that for a moment abandons the role of director (he is working on the new film 'The Matarese Circle') to present himself as artist. Inside the Congress Center of Estoril, from 5 to 14 november, you can admire the images chosen and processed by David Cronenberg and the Volumina staff starting with original film frames from his most famous movies: The Fly, Videodrome, The Dead Zone, Dead Ringers, Naked Lunch, Crash, Spider, and the recent Eastern Promises. The exhibition, curated by Domenico De Gaetano is completed by two 10-minute videos with famous sequences from Cronenberg's movies and a bilingual catalogue. One room is entirely dedicated to the installation RED CARS, in homage to the Ferrari, based on the artbook that was realized in 2005 and on rare archival footage..

9 September 2009

I am delighted and honoured to have Circos visualizations included as part of the Science Express project. Briefly, this is a public education effort lead by Max Planck institute to raise and foster science awareness and education to the public. The project is a 13 car train, lavishly repurposed into a rolling interactive science exhibition.

For those of you who can't experience the project first-hand, there is a wonderful virtual tour.

Circos - Circular Genome Data Visualization (800 x 348)

The design firm behind the exhibition is Archimedes. Visually, the project is stunning. Each car has an entirely different feel, which matches closely to the subject matter. For example, the nanotechnology car is tiled with mirrors, to give you the sense that you're inside an infinite lattice. Brilliant!

I am a strong proponent in making the product and knowledge garnered by science visually appealing &mdash for the same reason that presentations to public audiences should be both informative and engaging. Nature offers intrinsic beauty, be it as seen through its complexity (e.g. genome as an information warehouse) or reducible simplicity (e.g. supersymmetry in fundamental physical laws). Frankly, we don't need more dry and hypnogogic presentations - the facts and knowledge are there and easily accessed (though often mind-numbingly difficult to understand). What we need are more project like Science Express to attract the public, and potential future scientists, to science, and thereby persuade them that trying to understand inherently difficult things is rewarding and ... fun!

10 December 2008

I received my copy of the Chromosomes artbook by Volumina, for which I contributed genomic visualizations. Below are the scans of the front and the back of the book. David Cronenberg's son, Brandon Cronenberg, contributed his interpretation of chromosomes as machines of genetics - each page of the book has a unique chromosome interpretation in steam punk style.

Chromosomes - David Cronenberg - by Volumina (600 x 793)
11 October 2008

In collaboration with Volumina, Circos was used to generate illustrations for Chromosomes exhibition, an art book of still images from David Cronenberg films.

Illustrations created with Circos used in Chromosomes, an exhibition by David Cronenberg. (500 x 508)

I had the opportunity to contribute not only the art work, but text for this book as well.

Illustrations created with Circos used in Chromosomes, an exhibition by David Cronenberg. (800 x 267)

We fear the unknown. Monsters and creatures are words we give to the most frightening unknown of all — the biological. Things living — primitive, unpredictable, ravenous and without recourse to emotion or reason. Clutching reason and humanity, we congratulate ourselves for having departed those base instincts.

But our departure is neither recent nor complete. Inside each of us is a history of our evolutionary ancestors, written in our chromosomes. The ant has 2. The house fly, 12. Humans have 46, a dog has 78 and in a fern, there are over 1,000. Chromosomes are the superblocks of genetic organization and heredity. They are an organism's contact list of its evolutionary ancestors.

Many of these ancestors were not different from monsters and creatures that inhabit our nightmares, our fears and our movies. And as the lights come on, and projections from the screen yield to reality, our body harbors elements from a darker past. Like the Alu genetic element, a jumping-gene which repeatedly copies itself within our genome and a constant companion to our evolution for the past 65 million years. In every part of every chromosome is our creature heritage.

Although we emerged in human from our mother's womb, as embryos we exhibited our evolutionary history: we all had gills, a tail, and body hair. Lost or absorbed before birth, these signposts remind us that our ancestors are inside us, not just in stories or movies. It is only later that the brain, our species' most prized possession, develops and transforms us. In the last minute, we pass into humanity and into the world. Today, we tell stories of monsters and creatures. Tomorrow, we may take their place. Distant from now, our progeny will see our forms during development and say "What creatures we were." Movies will frighten by showing our forms. "Look, mommy, a smooth-skinned biped with wide eyes."

2 October 2008

I worked with Pearson publishers to create a cover for iGenetics (3rd ed) by Peter Russell.

Circos book cover - iGenetics by Peter Russell, 3rd ed (331 x 450)
12 June 2008

American Scientist cover, which I created with Circos, wins Silver EXCEL Award in the Cover Illustration category from Society of National Association Publications (SNAP).

Circos - Circular Genome Data Visualization (150 x 184)

"The cover graphic is a dramatic visual representation of some of the chromosomal connections between the dog and human genomes," Schoonmaker said. "It helps readers understand how physical differences between dogs and humans, and between one dog and another, can be so large, even though they share much genetically." (more).

9 August 2007

Circos appears on the cover of American Scientist (Sept/Oct issue). The image accompanies the article Genetics and the Shape of Dogs by Elaine Ostrander. Read about the figure.

Circos - Circular Genome Data Visualization (400 x 490)
23 November 2006

Circos appears in a New York Times graphic "Close up of the Genome, Species by Species by Species" in the NYT Science Section.

Circos in New York Times - Close up of the Genome, Species by Species by Species (400 x 370)