Circos is published in Genome Research. The paper comes with an attractive foldout poster! To cite circos, please use
Krzywinski, M. et al. Circos: an Information Aesthetic for Comparative Genomes. Genome Res (2009) 19:1639-1645.
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Figures 1, 2, 7 and 8 from Krzywinski, M. et al. Circos: an Information Aesthetic for Comparative Genomes. Genome Res (2009) 19:1639-1645.
ABSTRACT We created a visualization tool, called Circos, to
facilitate the identification and analysis of similarities and
differences arising from comparisons of genomes. Our tool is effective
in displaying variation in genome structure and, generally, any other
kind of positional relationships between genomic intervals. Such data
are routinely produced by sequence alignments, hybridization arrays,
genome mapping, and genotyping studies. Circos uses a circular
ideogram layout to facilitate the display of relationships between
pairs of positions by the use of ribbons, which encode the position,
size, and orientation of related genomic elements. Circos is capable
of displaying data as scatter, line and histogram plots, heat maps,
tiles, connectors and text. Bitmap or vector images can be created
from GFF-style data inputs and hierarchical configuration files, which
can be easily generated by automated tools, making Circos suitable for
rapid deployment in data analysis and reporting pipelines.